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Alchemy is a fascinating topic that is sadly not as widely presented in videogames as magic. Which is a pity: it’s a unique aesthetic that can be extremely immersive and fun if you provide it with gameplay mechanics that suit the very nature of alchemic tricks quite well.
In our list, we’ll show you ten games worthy of your time that play around with alchemy and similar topics.
Ready your mortar and pestle, sharpen your curiosity and step into the crucible. Let’s see what emerges from the mixture!
Without further ado, here's our list of six alchemic games that truly resemble the alchemic spirit that's so rarely presented in games!
Genre: Alchemy Sim | Developer: RocketBrush Games | Release Date: 2025
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When it comes to putting you into the shoes of a real medieval alchemist with his troubles and triumphs, Ways of Alchemy is perhaps the closest game we have on our list and a strong contender among the best alchemy games PC has to offer.
You start as an alchemist who receives an inheritance and slowly but surely starts his journey. You will have to deal with customers and their orders, eventually growing your reputation and gaining more orders. Some of these will be quite simple, some will require thinking harder than usual. You can grow ingredients for your brews or seek them out in faraway lands in expeditions, which will require hiring a loyal mercenary who can do the dirty work for you.
As you’re brewing your potions, you have two ways: to experiment or to follow the recipe. Experimenting may be suitable if you’re into true alchemic experience, while the recipes are quite simple to follow, but where’s the fun in that, right?
Your success may attract the attention of the king’s servants – the Tax Collector and the Inquisitor. You can play by their rules or try to trick them, which itself will lead to complicated objectives you have to deal with.
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Genre: Roguelite | Developer: Sengi Games | Release Date: 2022
If you ever wondered what it’s like to be an alchemist in a cursed world ruined by plague, The Serpent Rogue is the answer. This roguelite fuses potion-making with survival mechanics and puts you into a world where things get nasty very quickly.
You explore a shifting map, collect ingredients, and use your knowledge to concoct brews that affect not just you but the ecosystem.
Want to tame a beast or heal a stranger? You’ll need the right mixture and timing. In this regard, The Serpent Rogue is a unique take on alchemy games and one of the darkest ones. If you’re in a mood for this type of alchemic experience, do give it a go, it’s easily one of the best alchemy games.
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Genre: Alchemy Shop Sim | Developer: niceplay games | Release Date: 2022
Just like all perfect alchemy games, Potion Craft makes you step into the shoes of an alchemist. Potion Craft is a tactile, pleasant alchemy sim, which sets you up as the town’s go-to potion brewer, working in a medieval-style shop where everything from grinding ingredients to stirring the cauldron is done with your own hands.
The game is entirely based on complex systems but those systems are so fun and cleverly designed and satisfying to interact with that you’ll find yourself getting lost in the routine of mixing, experimenting and bargaining.
It’s a pure, well-contained experience that focuses on the process and craft of potion-making, paired with a simple economic loop.
You can experiment with weird recipes, upgrade your workshop and discover new alchemical paths on a hand-drawn map of sorts that even looks and feels like an actual alchemist’s notebook.
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Genre: Roguelike | Developer: Nolla Games | Release Date: 2020
Noita feels like the fever dream of a wild alchemist or an experimentator. Everything is simulated and every pixel reacts to your experiments. You’re not brewing potions here, but… let’s just say you are the potion.
Armed with spell-wands and chaotic ingredients, you will have to dig through underground biomes, unleashing explosive mixtures and transformative effects that often go out of control. Noita generously rewards your curiosity and creativity.
Noita’s unpredictability makes it incredibly frustrating at first, but eventually, you learn how things work in this world. And this is where the fun starts. We haven’t mentioned it, but Noita is truly addictive if you manage to get into it. You will never have two similar runs and, considering the unique type of the game, it’s more than welcoming — and it certainly earns its place among the best alchemy games for PC for those who love chaos and experimentation.
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Genre: Puzzle | Developer: Zachtronics | Release Date: 2017
In other games on our list, alchemy is an aesthetic, a vibe and a core that influences gameplay mechanics. In Opus Magnum, alchemy is a science of motion and precision. No wonder it’s considered one of the best alchemy games out there.
You play as an engineer-alchemist of the illustrious House Van Tassen, designing transmutation engines that assemble potions, poisons, and even mechanical arms.
The gameplay revolves around a beautiful programming-like interface where you build machines that carry, rotate and fuse alchemical components. Every puzzle has a thousand solutions, but elegance is its own reward. Perfect for those who are interested in automation, Opus Magnum is a wonderful game for those seeking out the alchemic elegance of transformation/transmutation mixed with tricky puzzles.
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Genre: Management Sim | Developer: PeDePe | Release Date: 2024
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This game leans into the daily grind of an alchemist who also happens to run a business. Alchemist Shop Simulator is part tycoon game, part resource management, and part magical shopkeeper fantasy.
Keeping the business afloat is the goal for you. Sounds simple? Well, you guessed it – it’s harder than it may seem at first!
That being said, keeping the business means regularly dealing with suppliers, stocking shelves, handling customer needs, and, of course, making the products that keep them coming back. It’s less about alchemic lore and more about logistics, which is great if you’re into this type of relaxing games.
But the alchemical spirit still regularly seeps through the cracks – definitely try it out if you’re into alchemy and looking for one of the best alchemy games on PC to play.
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Genre: Crafting | Developer: Reaktori Games | Release Date: 2024
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If you’re a player who wants RPG progression laced with bubbling cauldrons of all kinds and mushroom powders that can kill the whole town’s population, RPG Alchemy hits a very specific sweet spot, putting it among the best alchemy games for fans of deep crafting mechanics.
It combines classic RPG systems with a surprisingly robust potion crafting mechanic that’s more than just mixing red and blue vials.
You’ll gather ingredients, unlock recipes, and tinker with different effects while exploring the usual dungeon-delving and monster-fighting loops. The potions you brew can make or break a run, so the alchemy system isn’t just fluff — it’s the core of how you play.
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These four are not entirely rooted in alchemy, but still have certain conncetion to the alchemic process. That’s how few alchemic games there are – we have to look up those that are reminiscent of alchemy and can be rooted in entirely different vibes and aesthetics! These games may not focus on alchemy — but they play with its mechanics, systems, and soul.
Genre: Puzzle | Developer: Zachtronics | Release Date: 2011
Another game by Zachtronics in our list! This one is a bit different though. It might not look like alchemy on the surface, but SpaceChem is absolutely the spiritual cousin of turning lead into gold, just in a clean-room reactor instead of a castle room dedicated to your tricks
In this complex puzzle, you design complex reactors that combine atoms into new molecules, juggling timing, movement paths, and resource inputs. Every solution is a piece of invisible art, and just like a good transmutation, it always feels slightly magical when it finally works.
Spacechem is one of the games by Zachtronics, and people usually associate this studio with tricky puzzle games. While it’s definitely true about SpaceChem, you don’t have to be afraid of it – there are solutions available on YouTube you can analyze if things get too complex. It’s an abstract yet brilliant addition to the best alchemy games on PC lineup for puzzle fans.
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Genre: Adventure | Developer: Petums | Release Date: 2021
Papetura’s unique aspect is that it is hand-crafted and its entirely paper-sculpted adventure evokes the spirit of turning something boring, of mundane matter into something blazing and transcendent, exactly what alchemists dreamed of! It manages to be an exciting, unique take on the aesthetic.
The story is quiet, but strange, with glowing mushrooms, flickering shadows and mysterious beings that feel stitched together by candlelight.
Papetura is more focused on an emotional transmutation than mechanical crafting of matters, but still deeply rooted in the alchemical vibe — a quiet gem that stands out among the best alchemy games with a unique aesthetic. Short but sweet and extremely charming: give it a go and chances are you will fall in love with it.
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Genre: Crafting Sandbox | Developer: Headup | Release Date: 2023
Tinkertown’s charm lies in the creativity and experimentation, which is the heart of alchemy! Its gameplay loop can be described as “You gather, you build, you explore” — and of course you mix things up to see what happens.
Cooking, smithing or enchanting – Tinkertown is basically a very familiar sandbox experience. And yet, every crafting system gives off a soft alchemical glow. It’s not about strict, boring realism, it’s about the wonder of making something out of nothing — which is exactly why Tinkertown deserves a place among the best alchemy games for PC.
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Genre: Graveyard Management | Developer: Lazy Bear Games | Release Date: 2018
What if alchemy wasn’t noble, but a little shady? In Graveyard Keeper, your job is to keep the cemetery tidy… and maybe dabble in some unethical experiments on the side. No one is judging! It’s a perfect oddball addition to the best alchemy games list for players who like their potion-making with a side of grave robbing.
You brew potions, harvest questionable resources, and eventually start meddling with soul extraction, artificial resurrection, and other medieval science that’s definitely not approved by the local clergy. The alchemy here is messy, morally gray and perfectly fitting for a game about running a medieval funeral business.
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Some of the best alchemy games on PC and Steam include Potion Craft, Opus Magnum, Noita, The Serpent Rogue, and Ways of Alchemy. These games offer unique takes on potion making, alchemical experimentation, and resource management.
Potion Craft and Opus Magnum are standout titles for deep potion crafting. Potion Craft emphasizes hands-on, manual brewing using medieval tools, while Opus Magnum offers a complex system of alchemical machine design with endless creative possibilities.
Yes, all games from our list are presented on Steam!
The best alchemy games stand out through their immersive systems, unique visual styles, and the freedom they give players to experiment. Games like Noita add physics-based magic, while others like Ways of Alchemy blend storytelling with simulation mechanics.
Playing these games sure is fun! Especially considering how rarely alchemy is tackled as a topic in gaming. Fingers crossed we will see more of alchemy-based games in the near future!
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We consider alchemy a very fascinating topic and we poured a lot of enthusiasm into Ways of Alchemy by working on art, gameplay elements and 2D illustrations. If you’re making a game and can use a little help, do not hesitate to reach out at hello@rocketbrush.com and discuss your project in detail!
Let’s see what we can brew together!
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